Figure 5

Putative transmembrane structure of XPR1 and locations of the 6 residues responsible for receptor function. XPR1 has 4 putative extracellular loops (top) indicated as yellow bars in the mRNA. Codon positions for residues involved in entry are marked with arrows, and residues at these sites are shown for the 5 Mus alleles. "-" represents a deletion.