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Table 2 Neutralisation properties of different monoclonal antibodies against XMRV and MLV pseudotyped with three different envelopes.

From: Absence of xenotropic murine leukaemia virus-related virus in UK patients with chronic fatigue syndrome

   

Neutralisation of

Hybridoma1

Raised in

Isotype

XMRV

MLV(X)

Friend

Moloney

83A25'

Rat

IgG2A

Y (88)

Y (89)

ND

ND

24-7

Mouse

IgMK

N

N

ND

ND

48

Mouse

IgG2A

N

N

Y (95)

Y (83)

538

Mouse

IgM

N

N

N

Y (63)

603

Mouse

IgM

N

Y (96)

N

ND

609

Mouse

IgM

Y (71)

N

ND

ND

610

Mouse

IgM

N

Y (64)

ND

ND

613

Mouse

IgM

N

Y (91)

ND

ND

615

Mouse

IgM

N

N

ND

ND

  1. Y indicates neutralisation; N indicates no neutralisation; ND is not determined
  2. The number in brackets refers to the percentage neutralisation at the least diluted antibody concentration.
  3. 1 See references [13] and [14] for description of hybridoma cell lines