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Figure 5 | Retrovirology

Figure 5

From: Vpu serine 52 dependent counteraction of tetherin is required for HIV-1 replication in macrophages, but not in ex vivo human lymphoid tissue

Figure 5

Vpu S52A impairs HIV-1 replication in macrophages. Replication kinetics of wildtype NL4-3 and the indicated mutants in monocyte-derived macrophages and average levels of cumulative RT production by macrophages infected with the NL4-3 variants over a 20 day period. Values give averages +/- SEM of macrophages from three different donors with two independent virus stocks containing 1 ng p24 antigen. PSL, photon-stimulated luminescence.

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Retrovirology

ISSN: 1742-4690

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