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Table 1 Percent Nucleotide Identity and Amino Acid Similarity of HTLV4(1863LE) with other PTLV Prototypes1.

From: Ancient, independent evolution and distinct molecular features of the novel human T-lymphotropic virus type 4

 

HTLV-1 (ATK)

HTLV-2 (MoT)

HTLV-2 (Efe)

STLV-2 (PanP)

STLV-2 (PP1664)

HTLV-3 (2026ND)

STLV-3 (TGE2117)

Genome

62.0

70.7

70.8

70.4

70.8

63.2

63.5

LTR

45.2

63.2

62.5

62.5

64.7

42.9

45.7

gag

70.4 (82.0)

73.2 (85.9)

74.6 (85.9)

74.7 (85.0)

74.8 (86.3)

68.3 (83.6)

68.6 (82.7)

p19M2

(68.5)

(77.5)

(79.1)

(79.1)

(79.1)

(78.2)

(71.9)

p24C2

(90.2)

(91.6)

(91.6)

(91.5)

(92.6)

(89.3)

(90.2)

p15NC2

(81.5)

(84.0)

(81.5)

(81.5)

(84.0)

(76.5)

(74.1)

pro

59.0 (61.9)

66.7 (70.8)

66.5 (59.3)

70.0 (59.6)

67.0 (60.0)

64.1 (65.5.)

64.7 (60.0)

pol

63.9 (68.0)

71.4 (78.7)

71.5 (78.6)

71.1 (73.3)

71.2 (78.7)

64.9 (71.4)

65.5 (71.2)

env

65.8 (75.9)

73.1 (85.3)

72.8 (86.0)

72.0 (84.9)

72.0 (85.5)

68.5 (79.4)

67.2 (78.9)

SU3

(70.4)

(80.1)

(81.4)

(80.4)

(81.4)

(72.9)

(71.7)

TM3

(84.7)

(94.4)

(93.8)

(92.7)

(92.7)

(90.5)

(91.0)

rex

76.0 (63.9)

79.5 (74.1)

81.1 (75.3)

78.7 (65.2)

80.7 (68.8)

72.7 (59.4)

72.5 (57.7)

tax

75.9 (82.6)

80.0 (90.9)

80.1 (89.5)

76.7 (85.5)

77.2 (90.0)

74.2 (82.6)

74.1 (82.6)

  1. 1 amino acid similarity in parentheses; strain names given in parentheses
  2. 2 M, matrix protein; C, capsid; NC, nucleocapsid
  3. 3 SU, surface protein; TM, transmembrane