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Table 2 Virus titers of X/PMV LacZ pseudotypes on rodent and mink cells carrying variants of the Xpr1 receptor.

From: Six host range variants of the xenotropic/polytropic gammaretroviruses define determinants for entry in the XPR1 cell surface receptor

  

Log10 LacZ Pseudotype Titera

Mouse

Receptor

 

PMV

XMV

X/PMV

X/PMV

 
 

Cells

HIX

FrMCF

CAST-X

AKR6

XMRV

CasE#1

Cz524

A-MLV

Xpr1 n

NIH 3T3

5.2+/-0.3

5.1+/-0.3

0

0

0

0

0

5.2+/-0.5

Xpr1 sxv

NXPR-S

4.3+/-0.1

4.3+/-0.4

3.5+/-0.4

3.7+/-0.4

1.2+/-0.5

2.4+/-0.2

4.8+/-1.1

5.2+/-1.1

 

M. dunni

4.4+/-0.9

5.2+/-0.6

5.6+/-0.4

5.4+/-0.2

3.7+/-0.2

5.3+/-0.4

5.8+/-0.1

4.9+/-0.1

Xpr1 c

NXPR-C

0

0

3.5+/-0.5

2.8+/-0.3

0.5+/-0.3

0

1.0+/-0.4

4.2+/-0.9

Xpr1 p

M. pahari

0

0

4.7+/-0.3

4.5+/-0.4

3.3+/-0.3

4.5+/-0.4

0

3.9+/-0.4

 

Hamster

0

0

1.1+/-0.5

0

0

0

0

3.7

 

Rat

4.6+/-0.1

0.5+/-0.5

5.2+/-0.4

5.1+/-0.1

3.1+/-0.6

5.1+/-0.5

1.7+/-0.6

4.7+/-0.6

 

Mink

5.5+/-0.3

5.6+/-0.1

5.3+/-0.3

5.1+/-0.3

4.2+/-0.4

5.1+/-0.3

5.0+/-0.6

4.5+/-0.9

  1. aMeasured as the number of cells positive for β-galactosidase activity in 100 ul of virus. Where no SD is given, infectivity was only tested once. 0, no positive cells in cultures infected at least 3 times with 0.1 ml of undiluted pseudotype stock.