Figure 3
From: Perinatal acquisition of drug-resistant HIV-1 infection: mechanisms and long-term outcome
Resistance analysis of HIV-1 RNA and DNA from the mother-child pair #12. Time course of HIV-1 RNA and DNA levels in children with resistance mutations as detected by population-based sequencing and clonal analysis (box). Antiretroviral treatment is indicated above. Maternal antiretroviral treatment at delivery, viral RNA load, and the number of wild-type (WT) or resistant clones are indicated. In the phylogenetic tree, maternal viral clones are represented by circles and newborn viral clones by squares. M indicates the time to genotype testing in month. Wild-type quasispecies are represented by open circles and squares, and resistant quasispecies by full circles and squares. HIV-1 RNA results are in blue, and HIV-1 DNA results are in pink. The arrow indicates the maternal viral clone closest to the infant's quasispecies.