Patient | Tissuea | Env clone | MDM entryb | b12 IC50c | b6 IC50c | sCD4 IC50c | PS IC50c |
---|---|---|---|---|---|---|---|
MACS2 | FL | 8–12 | 35478 | 3.37 | > 20 | 1.03 | 80.9 |
 |  | 9–15 | 1765 | 1.15 | > 20 | 0.22 | 76.4 |
 | LN | 10–15 | 13001 | 0.99 | > 20 | > 20 | < 50 |
 | SP | 6–18 | 59224 | 10.89 | > 20 | > 20 | < 50 |
MACS3 | FL | 12–27 | 13810 | > 20 | 1.87 | 1.10 | < 50 |
 |  | 5 | 3402 | > 20 | 6.78 | 0.40 | < 50 |
 | LN | 2 | 1957 | > 20 | > 20 | 3.22 | < 50 |
 |  | 20 | 16658 | > 20 | > 20 | > 20 | < 50 |
UK1 | FL | 2–13b | 4378 | 0.05 | > 20 | 5.44 | < 50 |
 | SP | 6–20 | 812689 | 0.03 | > 20 | 2.39 | 124.2 |
 |  | 20 | 35723 | 0.03 | > 20 | 0.27 | 230.2 |
UK7 | FL | 6–24 | 9659 | 5.53 | > 20 | 7.68 | 145 |
 |  | 1–4 | 13207 | 11.37 | > 20 | > 20 | 128 |
 | isolate | br34 | 496588 | 0.26 | > 20 | 0.45 | 332.2 |
 | LN | 7–6 | 5260 | 5.55 | > 20 | > 20 | < 50 |
controls | Â | YU2 | 38052 | 5.47 | > 20 | 1.14 | 72.4 |
 |  | YU2 N386D | 114755 | 2.79 | > 20 | 0.45 | 115.2 |
 |  | JRFL | 215305 | 0.18 | > 20 | 3.72 | 107.3 |
 |  | JRFL N386D | 320642 | 0.09 | > 20 | 6.05 | 92.7 |