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Figure 2 | Retrovirology

Figure 2

From: Pathogenic infection of Macaca nemestrinawith a CCR5-tropic subtype-C simian-human immunodeficiency virus

Figure 2

Mucosal CD4+ T-cell depletion due to SHIV-1157ipd3N4 infection. (A) Total lymphocytes isolated from duodenal biopsies from infected pig-tailed macaques were analyzed by flow cytometry for CD3+CD4+ T cells. CD4+ T-cell percentages were obtained by gating on CD3+ T cells and then lymphocytes. (B) Histogram plots showing a comparison of CD4+ T-cell percentages in mucosal tissues of macaque L03165. Duodenal and colonic biopsies, and BAL samples, were taken concurrently at the specified timepoints pre- and post-inoculation. (C) CD4:CD8 ratios in the duodenum were generated by using the percentages of total CD4+ and CD8+ T cells.

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