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Table 1 Immunization regimen

From: Role of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vectors

  

weeks post immunization

 

monkeys

0

4

8

12

group 1

12127

SCIV [VSV-G]

SCIV [VSV-G]

Ad5-SIV

Ad5-SIV

 

12128

tonsillar

tonsillar

tonsillar

tonsillar

 

12131

1.8 × 109, a

1.2 × 108, a

1 × 1011, b

1 × 1011, b

 

12137

    

group 2

12133

SCIV [VSV-G]

 

Ad5-SIV

 
 

12136

intravenous

 

intramuscular

 
 

12142

2 × 109, a

 

6 × 1011, b

 
 

12143

    

group 3

12132

SCIV [VSV-G]

 

SCIV [MLV]

 
 

12138

intravenous

 

intravenous

 
 

12139

2 × 109, a

 

3 × 107, a

 
 

12140

    

group 4a

12129

  

Ad5GFP tonsillar

Ad5GFP tonsillar

 

12130

  

1 × 1011, c

2 × 1011, c

group 4b

12134

  

Ad5GFP intramuscular

 
 

12141

  

6 × 1011, c

 
  1. ainfectious units/ml
  2. bnumber of particles per construct
  3. cnumber of particles