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Figure 2 | Retrovirology

Figure 2

From: Role of complement and antibodies in controlling infection with pathogenic simian immunodeficiency virus (SIV) in macaques vaccinated with replication-deficient viral vectors

Figure 2

IgG response to the viral env-proteins. During vaccination, SIV-specific IgG antibodies targeting the envelope were determined in all vaccine groups and in the control group after challenge with SIVmac239. For this assay SIVmac251 infected HSC-F were incubated with heat-inactivated sera from vaccinated and infected animals. SIV-specific antibodies bound to infected T-cells were stained with a FITC-labelled anti-human IgG and determined by flow cytometry. Values are given as mean fluorescence intensities (MFI). Dotted arrows mark points in time of boosts and additional asterisks refer to boosts of group 1 only, whereas the black arrow indicates the point in time of challenge.

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