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Table 1 Animal Information and analysis using the acute HIV-1 infection model.

From: Nef gene evolution from a single transmitted strain in acute SIV infection

Animal Index

-sample date

viral load (copies/ml)

Number of Sampled Sequences

Divergence

Diversity

Variance

Max.

HD

Sequence

Identity

Estimated

days post

infection

(95% CIs)

χ2goodness of fit P value

r00065-day4

18,600

31

0.016%

0.033%

0.027%

2

87.1%

14 [4–35]

0.79

r00065-day7

1,660,000

41

0.018%

0.037%

0.043%

3

87.8%

16 [6–34]

0.52

r00065-day11

90,800,000

50

0.013%

0.025%

0.022%

2

90.0%

11 [4–25]

0.82

r00065-day18

39,750,000

31

0.0081%

0.016%

0.015%

2

93.5%

7 [1–25]

0.93

r98018-day7

20,000

33

0.0077%

0.015%

0.014%

2

93.9%

7 [1–23]

0.93

r98018-day14

12,380,625

67

0.026%

0.052%

0.055%

4

82.1%

22 [12–37]

0.70

r98018-day21

1,391,000

69

0.016%

0.033%

0.057%

5

91.3%

14 [7–27]

0.86

  1. Animal information including time of sampling, viral load, and number of nef sequences obtained. For each sample, we calculate divergence, diversity, variance, maximum HD, and sequence identity. Estimated days since infection with 95% confidence intervals and p-values were calculated via Maximum Likelihood method to fit a Poisson distribution to Hamming distance distribution from the founder strain and the goodness of fit through a Chi-Square statistic.