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Figure 2 | Retrovirology

Figure 2

From: Microarray study reveals that HIV-1 induces rapid type-I interferon-dependent p53 mRNA up-regulation in human primary CD4+T cells

Figure 2

Hierarchical clustering and gene ontology analysis of microarray data. (A) A hierarchical clustering of the 56 genes that are modulated (down- or up-regulated) by either NL4-3 wt or NL4-3 ICAM-1+ at 8 h post-infection (as determined by a two-fold threshold) has been defined using the correlation function of GeneSpring 6.0. (B) A hierarchical clustering of the 363 genes that are modulated (down- or up-regulated) by either NL4-3 wt or NL4-3 ICAM-1+ at 24 h post-infection (as determined by a two-fold threshold) has been defined using the correlation function of GeneSpring 6.0. (C) Hierarchical clustering of genes belonging to selected Gene Ontology categories identified by a Gene Ontology overrepresentation analysis as being significantly enriched within the list of genes modulated by HIV-1 is shown.

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Retrovirology

ISSN: 1742-4690

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