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Figure 6 | Retrovirology

Figure 6

From: TLR2 and TLR4 triggering exerts contrasting effects with regard to HIV-1 infection of human dendritic cells and subsequent virus transfer to CD4+T cells

Figure 6

TLR2 and 4 triggering increases viral entry in IM-MDDCs. A) IM-MDDCs were either left untreated (mock) or treated with TLR2 and 4 ligands for 2 hours and washed twice. Then, cells were pulsed with NL4-3/Balenv for 15, 30 and 60 min at 37°C. Next, the virus-cell mixture was washed extensively with PBS and trypsinized to remove uninternalized virus. Finally, cells were lysed and the p24 contents were measured by ELISA. Numbers depicted above bars represent fold increase relative to p24 levels in untreated control cells (considered as 1). The data shown represent the mean ± standard deviations of triplicate samples from 3 different donors.

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Retrovirology

ISSN: 1742-4690

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