Skip to main content

Table 3 Origin of previously described MSRV sequences

From: Analysis of transcribed human endogenous retrovirus W env loci clarifies the origin of multiple sclerosis-associated retrovirus envsequences

MSRV sequences HERV-W source locus/loci Number of nucleotide mismatches
env   no recombinations recombinations
AF127227 (544 bp) 3q23 1 (1.84/kb) n.a.
AF127228 (1932 bp) Xq22.3 4 (2.07/kb) n.a.
AF127229 (2004 bp) 3p12.3/18q21.32 94 (46.91/kb) 3 (1.5/kb)
AF123882 (2477 bp) 15q21.3 5 (2.02/kb) n.a.
AF331500 (1629 bp) Xq22.3/5p12 31 (19.03/kb) 5 (3.07/kb)
AF123881 (1511 bp) 3q26.32 2 (1.32/kb) n.a.
  1. Previously published MSRV sequences were assigned by BLAT searches to corresponding HERV-W elements in the human genome. The accession number and length (base pairs, bp) of published MSRV clones are provided in the left column. The best matching HERV-W locus or loci (in case of recombined sequences) are indicated in column 2, and the number of nucleotide mismatches between MSRV sequences and the best matching genomic HERV-W elements in column 3. Note that for the recombined sequences, the number of nucleotide mismatches after assuming recombinations is markedly reduced. The average number of nucleotide differences of the 6 analyzed MSRV sequences to their best matching genomic HERV-W locus/loci was 1.97/kb. n.a., not applicable