Increased neutrophil apoptosis in chronically SIV-infected macaques

Retrovirology

Table 1 Characteristics of the study population ^a

	SIV^-	SIVΔnef	SIV⁺ slow progressors	SIV⁺ moderate progressors
	(n = 6)	(n = 4)	(n = 6)	(n = 5)
PMN count ^b	1840 ± 259	1693 ± 325	1956 ± 252	1685 ± 245
Lymphocyte count ^b	3104 ± 212	2970 ± 451	3317 ± 608	2354 ± 230
CD4⁺ count ^b	1127 ± 232	1086 ± 320	848 ± 149	317 ± 79 ^{d, e}
CD8⁺ count ^b	651 ± 161	778 ± 184	1077 ± 277	1050 ± 232
Viral load ^c	0	1.22 ± 0.42	38 ± 19 ^{d, e}	1706 ± 699 ^{d, e, f}

^a Monkeys were infected intravenously with 10 AID₅₀ of the non-pathogenic nef-deleted SIVmac251 isolate (SIVΔnef) or the pathogenic strain SIVmac251 (SIV⁺) and were studied 8 months later.
Values are means ± SEM.
^b PMN, lymphocytes, CD4⁺ and CD8⁺ counts are expressed per microliter.
^c Viral load is expressed as 10² copies per milliliter.
^d Significantly different from healthy controls (SIV^-) (p < 0.05).
^e Significantly different from SIVΔnef (p < 0.05).
^f Significantly different from SIV⁺ slow progressors (p < 0.05).

ISSN: 1742-4690