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Figure 2 | Retrovirology

Figure 2

From: In vivo expression of the HBZ gene of HTLV-1 correlates with proviral load, inflammatory markers and disease severity in HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Figure 2

Correlation between HTLV-1 proviral load and HTLV-1 mRNA load in HTLV-1 infected individuals. A. The HTLV-1 HBZ mRNA load was significantly correlated with HTLV-1 proviral load in HAM/TSP patients alone (P = 0.0005, r = 0.470 by Spearman rank correlation analysis), HCs alone (P = 0.0013, r = 0.528) and all groups combined (P < 0.000001, r = 0.686) but not in ATL patients (P = 0.300, r = 0.345). B. The tax mRNA load correlated with the HTLV-1 proviral load in HCs (P = 0.045, r = 0.444), ATL patients (P = 0.045, r = 0.673) and both group combined (P < 0.01, r = 0.365) but not in HAM/TSP patients (P = 0.411, r = 0.210). The zero value of tax gene transcripts did not appear in the figures. Correlations were examined by Spearman rank correlation analysis.

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