DNA double strand break repair enzymes function at multiple steps in retroviral infection

Retrovirology

Table 1 The number of 3' abnormal junctions of the HIV-1 provirus

	ATM(-)	ATM(+)	Mre11(-)	Mre11(+)	NBS1(-)	NBS1(+)	Artemis(-)	MRC5SV
Insertions	8	1	11	2	5	1	9	1
Insertions + Deletions	0	0	0	0	1	0	1	0
Deletions	2	3	2	3	2	5	1	7
Total junctions	161	151	147	144	145	168	136	216
P value	0.012		0.023		0.035
	(0.0046)	(0.80)	(0.00005)	(0.34)	(0.013)	(0.86)	(0.0003)

The P values under the columns of the deficient cell lines are for comparison of the number of junctions with only insertions or both insertions and deletions to that of the corresponding complemented cell lines. The numbers in parentheses under the table represent the P values compared to the control MRC5SV cells.

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