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Table 2 Sensitivity, specificity, positive and negative predictive values and odds ratio for the anti-Env antibody LIPS test in diagnosing HAM/TSP

From: Anti-HTLV antibody profiling reveals an antibody signature for HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)

Comparisons Sensitivity Specificity PPV NPV OR (95% CI)
> 100,000 LU      
HAM/TSP vs ATLL & Asymp 81% 72% 75% 79% 11.1 (3.7–33.5)
HAM/TSP vs ATLL 88% 58% 75% 75% 10.5 (2.8–39.4)
HAM/TSP vs Asymp 91% 55% 75% 80% 12.0 (2.8–51.4)
> 200,000 LU      
HAM/TSP vs ATLL & Asymp 85% 70% 70% 85% 13.1 (4.1–42.0)
HAM/TSP vs ATLL 90% 56% 70% 83% 11.7 (2.8–47.9)
HAM/TSP vs Asymp 93% 52% 70% 87% 15.2 (3.0–77.9)
  1. Note. PPV, positive predictive value; NPV, negative predictive value; OR, Odds ratio; CI, confidence interval.