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Table 1 The α-helical content of P1 & P5 alone or in the presence of N36 & LZ

From: Peptide P5 (residues 628–683), comprising the entire membrane proximal region of HIV-1 gp41 and its calcium-binding site, is a potent inhibitor of HIV-1 infection

 

[θ]222

(10-3deg cm2dmol-1)

 

[θ]222

(10-3deg cm2dmol-1)

N36

-6

LZ

-4

P1

-11

P5

-15

P1+N36

-17

P1+LZ

-21

P5+N36

-21

P5+LZ

-23

aT20

-2

bT20+N46

-9

  1. Note: Peptides were all chemically synthesized; a: from[20]; b: from [36]
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Retrovirology

ISSN: 1742-4690

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