Figure 6
From: Homonuclear 1H NMR and circular dichroism study of the HIV-1 Tat Eli variant
Tat Bru (A), Tat Mal (B), and Tat Eli (C) 3D structures. Region I is depicted in red, region II (cysteine-rich region) in orange, region III in yellow, region IV (basic region) in green, region V in light blue, region VI (residues 73–86/87) in blue and for Tat Eli the extra C terminal residues are in pink. The three Tat structures displayed a similar folding characterized by a core region composed of a part of region I with the highly conserved Trp 11 while the functional region II, IV and V are well exposed to the solvent. The extra residues in the C-terminus of Tat Eli protrude from a groove between the basic region and the cysteine-rich region and are exposed to solvent.