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Table 1 Effects of 2 nM β-estradiol on HIV replication in the presence and absence of 50 nM D4T*

From: beta-estradiol attenuates the anti-HIV-1 efficacy of Stavudine (D4T) in primary PBL

 

Mean normalized pg/ml (%)**

Standard Error

virus alone (VA)

100

5.4

β-estradiol

74

5.4

D4T

33

5.4

D4T+β-estradiol

74

5.4

no virus control

3.9

6.9

  1. *Data presented represents the combined results of 8 independent experiments on PBL from 8 different donors. For each experiment all data points were the averages of three cultures wells run in triplicate. Virus replication was assessed by p24Ag ELISA of culture supernatants.
  2. **Data is presented as the mean of least squares normalized to "virus alone."
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Retrovirology

ISSN: 1742-4690

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