Figure 1From: beta-estradiol attenuates the anti-HIV-1 efficacy of Stavudine (D4T) in primary PBLChange in D4T concentration required to overcome the efficacy impairment caused by β-Estradiol. A series of D4T dilutions were applied to HIV-1 infected PBL with or without 2 nM β-estradiol. The viral concentrations were measured with p24 ELISA, then normalized to the viral concentration from HIV-1 alone control. The data presented represents averages and standard deviations (error bars) from experiments performed on 4 different donors, each run in duplicate. Stippled, β-estradiol +D4T; clear, D4T alone.Back to article page