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Figure 6 | Retrovirology

Figure 6

From: Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope

Figure 6

Substitution of a single arginine residue with alanine yields an improved inhibitor. The syncytium inhibition activity of the peptides Pcr-400, PBLV-391 and the derivative peptide PBLV-R403A was examined. The percentage syncytium inhibition following co-incubation of cells with the peptides is shown. Syncytia were counted in 10 low-power light microscope fields. Data points show the mean ± SD of triplicate assays. The asters show the data points for which the p values were calculated (see main text).

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Retrovirology

ISSN: 1742-4690

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