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Figure 5 | Retrovirology

Figure 5

From: Highly specific inhibition of leukaemia virus membrane fusion by interaction of peptide antagonists with a conserved region of the coiled coil of envelope

Figure 5

Homology model of the BLV core coiled-coil and the interacting LHR. The protein sequence of BLV TM was modelled onto the HTLV-1 TM ectodomain structure (PDB ID 1MG1). (A) The predicted BLV core coiled-coil is shown as a space-filling model in grey with the LHR in green. (B) Detail of the coiled coil in blue, grey and red, with the C-terminal section mimicked by PBLV-391 shown as a green ribbon, the predicted position of relevant side chains are shown as sticks. The membrane proximal region is uppermost. The arrowhead marks the position of Leu404.

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