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Figure 4 | Retrovirology

Figure 4

From: HLA-C increases HIV-1 infectivity and is associated with gp120

Figure 4

Cell fusion of HLA-C silenced HeLa-Env cells with HeLa-P4.2 target cells. Analysis of syncytia formation by co-cultivating HLA-C silenced (+) and non-silenced (-) HeLa-LAI and HeLa-NDK cells with target HeLa-P4.2 cells, expressing CD4 and CXCR4. The number of syncytia formed is lower (p < 0.01) using HLA-C silenced HeLa-LAI cells. Fusion efficiency of HeLa-NDK cells is not significantly affected by HLA-C silencing.

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