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Table 1 Putative HIV receptor expression on oral keratinocytes

From: Oral keratinocytes support non-replicative infection and transfer of harbored HIV-1 to permissive cells

Receptor

Function

TE

(Mean ± SD)a

TERT-2

(Mean ± SD)b

CD104 (β4 integrin)

transmembrane protein expressed predominantly in epithelial cells [32]

80 ± 11

83 ± 4

HSPGs

HIV gp120 binding [70]

13 ± 7

91 ± 20

GalCer

HIV gp120 binding [71]

4 ± 0.1

< 1

CD4

HIV gp120 binding [72]

< 1.0

< 1

CXCR4

X4-tropic chemokine co-receptor [73]

< 1.0

3.5 ± 2

CCR5

R5-tropic chemokine co-receptor [73]

< 1.0

< 1

CD3, CD11a/LFA-1, CD32, CD64, CD89, DC-SIGN, Macrophage Mannose Receptor

 

< 1.0

Not tested

Human fibroblast

 

4 ± 4

Not tested

  1. a Mean ± SD of four independent experiments (1 experiment from tissue no. 164 and 193, and 2 experiments from tissue no. 196)
  2. b Mean ± SD of three independent experiments