Recombination between uDNA-derived and iDNA-derived genomes. Jurkat cells were simultaneously infected with D116N-YFP and WT-CFP viruses and a virus transfer experiment performed as in Figure 4. The appearance of GFP+ target cells is strictly dependent upon copackaging of YFP and CFP genomes into virions during virus assembly in producer cells and reverse transcription during second round infection of target cells . Numbers represent the percentage of cells in each quadrant. Data are representative of multiple independent experiments.