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Figure 4 | Retrovirology

Figure 4

From: Variation in HIV-1 R5 macrophage-tropism correlates with sensitivity to reagents that block envelope: CD4 interactions but not with sensitivity to other entry inhibitors

Figure 4

Sensitivity of HIV-1 R5 envelopes to 2G12. Pseudovirions carrying envelopes encoded by envelope genes amplified from patient samples were tested for sensitivity to inhibition by 2G12. Macrophage-tropic envelopes (light symbols) and non-macrophage-tropic envelopes (dark symbols) were examined. Statistical analysis showed a significant correlation between macrophage-tropism and sensitivity to 2G12.

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