Table 3 Assignment of clones from infected PBMCs into groups and subgroups based on mutational patterns
From: Highly diversified multiply drug-resistant HIV-1 quasispecies in PBMCs: a case report
Group | Mutational pattern (% representation) | Subgroup | Predominant mutations In PR partially mutated sites | Predominant mutations In RT | Frequency (%) | |
|---|---|---|---|---|---|---|
100% mutated sites | Partially mutated sites | |||||
A | PR90M/46I (40.4) | 1 | 41L/43E/44A/98G/118I/208Y/210W/214F/215Y/228R/283I | 181C/190A/219R | 4.6 | |
2 | 41K/46I/90M | 181C/184V/190A/219R | 4.6 | |||
3 | 41K/46I/90M | 184V/190A/219R | 1.8 | |||
4 | 41K/46I/90M | 184V | 18.3 | |||
5 | 41K/46I/90M | 101E/Q/108I/184V | 2.8 | |||
6 | 41K/46I/90M | 101E/Q/108I/181C/184V/190A | 1.8 | |||
7 | 36T(V)/41K/46I/90M | 184V | 1.8 | |||
8 | 35D/46I/90M | 181C/190A/219R | 0.9 | |||
9 | 35D/46I/90M | 184V | 3.7 | |||
B | PR82A/46L/54V/64V (45.9) | 10 | 41K/46V/54V/64V/82A | 41L/43E/44A/98G/118I/208Y/210W/214F/215Y/228R/283I | 184V | 10.1 |
11 | 41K/46V/54V/64V/82A | 181C/190A/219R | 6.4 | |||
12 | 41K/46V/54V/64V/82A | 181C/184V/190A/219R | 5.5 | |||
13 | 41K/46V/54V/63H/64V/82A | 181C/184V/190A/219R | 0.9 | |||
14 | 41K/46V/54V/64V/82A | 69N/101E/108I/181C/184V/190A/219R | 2.8 | |||
15 | 41K/46V/54V/64V/82A | 101E/184V | 1.8 | |||
16 | 35D/46V/54V/64V/82A | 184V | 3.7 | |||
17 | 35D/46V/54V/64V/69Y/82A | 101E/108I/184V | 1.8 | |||
18 | 35D/46V/54V/64V/69Y/82A | 74V/101E/108I/181C/184V/190A/219R | 1.8 | |||
19 | 35D/46V/54V/64V/69Y/82A | 69N/101E/108I/184V | 2.8 | |||
20 | 35D/46V/54V/64V/69Y/82A | 69N/101E/108I/181C/184V/190A/219R | 4.6 | |||
21 | 35D/46V/54V/64V/69Y/82A | 181C/184V/190A/219R | 4.6 | |||
22 | 35D/46V/54V/64V/69Y/82A | 181C/190A/219R | 1.8 | |||
23 | 46V/54V/64V/69Y/82A | 101E/108I/181C/184V/190A/219R | 0.9 | |||
C | PR90M/46L (5.5) | 24 | 35D/46L/90M | 41L/43E/44A/98G/118I/208Y/210W/214F/215Y/228R/283I | 181C/190A/219R | 0.9 |
25 | 35D/46L/54V/64V/69Y/90M | 181C/190A/219R | 0.9 | |||
26 | 36I/41K/46L/90M | 184V | 0.9 | |||
27 | 41K/46L/54V/90M | 184V | 0.9 | |||
28 | 41K/46L/54V/64V/90M | 184V/219R | 1.8 | |||
D | PR82A/46I (4.6) | 29 | 41K/46I/69Y82A | 41L/43E/44A/98G/118I/208Y/210W/214F/215Y/228R/283I | 101E/108I/181C/190A/219R | 2.8 |
30 | 41K/46I/82A | 184V | 0.9 | |||
31 | 35D/46I/54V/82A | 184V | 0.9 | |||