Figure 1

The Pvt1 and the Myc loci have separate and distinct common integration sites. Screen print of a customized version of the UCSC genome website browser (mouse February 2006 (mm8) genome assembly) depicting the Myc and the Pvt1 locus in the mouse. Numbers at the top, nucleotide position at chromosome 15. Green squares indicate insertion sites. Below them are the exon-intron structures of Myc and Pvt1, respectively. Pvt1 is represented by two reference sequences, AK090048 and Z11981, which do not share any sequence homology, but there are other transcripts as well: Below the reference sequences, there are various mouse mRNAs from GenBank. In this representation, the myc exons (thin vertical bars) are compressed. Introns are represented by horizontal lines, with the arrows denoting direction of transcription. Myc transcription is from left to right, and most Pvt1 transcripts are also from left to right.