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Table 1 Virus titers of ecotropic gammaretroviruses on mouse cells and mouse or ferret MA139 cells transfected with mCAT-1 or dCAT-1

From: Role of receptor polymorphism and glycosylation in syncytium induction and host range variation of ecotropic mouse gammaretroviruses

 

Log10 Virus Titera

Cellsb

F-S MLV

FBLV

Spl574

MoMLV

NIH 3T3

5.7

5.3

3.2

5.1

M. dunni

5.1c

4.1

5.1c

2.2

M. dunni (mCAT-1)

5.5c

5.5

5.2c

4.5

FerrM (mCAT-1)

4.5

4.2

0.3

3.9

FerrD2 (dCAT-1)

4.7c

4.2c

0.8

4.2

  1. aVirus titers were determined by the XC overlay test in which the indicated cells were infected with virus dilutions, irradiated and overlaid with XC cells to identify virus infected cells [9]. Titers represent the number of XC PFU in 0.2 ml. Infections were done four times; results shown are from one representative experiment. Bold figures represent titers reduced by more than 95% (1.3 log10) relative to NIH 3T3 (for MoMLV) or M. dunni cells (for Spl574).
  2. bCAT-1 gene expressed in transfected cells is given in ().
  3. cSyncytia were observed 2 days after virus infection.