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Table 2 Verapamil inhibits the effect of ABCB4 expression on lentiviral vector infectivity.

From: Alteration of viral lipid composition by expression of the phospholipid floppase ABCB4 reduces HIV vector infectivity

Pseudotyping

ABCB4 mutant

ABCB4 wild type

VSVg (n = 2)

6.1 * 104

8.2 * 104

GP64 (n = 1)

9.1 * 104

7.7 * 104

  1. Viral vectors pseudotyped with VSVg or GP64 were produced in the presence of wild type or mutant ABCB4 in the presence of Verapamil. Titers are expressed as HeLa transducing units/ml.