Figure 3
Transcriptional signatures in HIV-infected PBMC in vivo. Per-cell viral RNA expression levels as calculated after assignment of specimens to the transcriptional classes ILow, IIMedium and IIHigh (table 1). Only unique specimens devoid of cells of a higher expression category were analyzed in each expression class. Thus unique class-ILow positive samples are devoid of class-IIMedium and class-IIHigh cells, unique class IIMedium specimens are devoid of class-IIHigh. Data were pooled from all patients because separate analyses of single patients showed similar distributions (data not shown). "Box and whiskers" show the ranges, medians and interquartile ranges of the data displayed by single symbols. Numbers below columns indicate medians (quartiles), p-values above columns show significance levels of paired (Wilcoxon signed rank test) comparisons. *** indicates p-values < 0.0001 of (unpaired) Mann-Whitney testing between neighbouring columns.