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Table 1 Neutralization in single cycle assays (50% inhibitory concentrations (μg/ml))a

From: The carbohydrate at asparagine 386 on HIV-1 gp120 is not essential for protein folding and function but is involved in immune evasion

 

LAI (whole virus)

JR-FL (pseudovirus)

 

wt

N386D

wt

N386D

2G12

1.93

>10

0.66

7.96

CD4-IgG2

0.78

0.28

0.17

0.11

b12

0.62

0.079

0.043

0.020

b6

>10

>10

>10

>10

  1. a The IC50 values were derived from the experiment in fig. 6 as described in the materials and methods section.