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Table 4 Replication of SIV variants generated in human 293T cells.

From: Role of the long cytoplasmic domain of the SIV Env glycoprotein in early and late stages of infection

Virus a

JC-53B titer b IU c /ml

ELISA (p27) b ng/ml

IU/ng c

(fold difference from SIVmac239)

SIVmac239

1 × 103

306

3

-

SIVmac239T

6 × 103

101

59

20

SIVmac18

1 × 103

117

9

3

SIVmac18T

3 × 104

65

461

154

  1. aViruses were obtained simultaneously after transfection of 293T cells with equimolar amounts of DNA.
  2. bAssays are described in Methods.
  3. cInfectious units