Figure 1From: Role of the long cytoplasmic domain of the SIV Env glycoprotein in early and late stages of infectionSchematic representation of envelope gene products of cloned SIV adapted or not adapted to human cells. SIVmac239 has a full length 164 amino acid cytoplasmic tail (CT) [64]. The 239T construct has a truncated CT of 18 amino acids. A site-specific C to T mutation present in the 239T env gene changed a CAG glutamine codon at position 734 to a TAG termination codon. SIVmac18T contains a single amino acid substitution A239T in the SU domain designated 18 [25]. Numbers represent amino acid residues. Shaded boxes represent the hydrophobic transmembrane-spanning regions.Back to article page