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Figure 1 | Retrovirology

Figure 1

From: Compartmentalization of the gut viral reservoir in HIV-1 infected patients

Figure 1

Bootstrap Neighbor-Joining tree of the sequences of the Nef encoding region obtained from gut tissues. Nef sequences clustered by individual patients (indicated by colors). Closer examination of these sequences revealed clustering of Nef sequence by tissue compartment (esophagus (E), stomach (S), duodenum (D), colorectum (C) and PBL) within patients, indicative of compartmentalization of viral replication in the gut, resulting in the evolution of different HIV-1 quasispecies in different parts of the gut. (Bootstrap values > 70 are indicated.)

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