Mortality associated with HIV-1, HIV-2, and HTLV-I single and dual infections in a middle-aged and older population in Guinea-Bissau

Table 5 Mortality rates and mortality rate ratios for HIV, irrespective of HTLV-I status. MRs and MRRs below and above 45 years of age are compared

	HIV-1 and HIV-1 + HIV-2 dually infected*			HIV-2 single infected^†
Age group	Mortality rate/1000 pyo	MRR^‡	95% CI^§	Mortality rate/1000 pyo	MRR^‡	95% CI^§
MEN
<45	45.1(6.4–320)	12.0^#	1.4,99.7	17.9(4.5,71.6)	4.8^#	1.0,23.6
> = 45	176(73.2–422)	4.6	1.9,11.1	74.6(54.7,102)	1.5	1.1, 2.2
Test of homogeneity of effect modification of age			p = 0.41			p = 0.18
WOMEN
<45	46.4(6.5–329)	17.1^#	2.1,142	33.4(15.0,74.3)	12.3^#	4.0,38.9
> = 45	120(49.8–288)	5.4	2.2,13.1	66.3(51.1,85.9)	1.9	1.4,2.6
Test of homogeneity of effect modification of age			p = 0.32			p < 0.005

*Including both HIV-1 single and HIV-1 + HIV-2 dual infections.
^†Including only HIV-2 single infections.
^‡ MRR = Mortality rate ratio, comparing with HIV-negative.
^§ CI = confidence interval.
^#The MRRs are different from those in Table 4 as the HIV-1 single and HIV-1 + HIV-2 dually infected have been grouped together in this Poisson model (see statistical methods)

ISSN: 1742-4690