Table 1 Combined HR1-HR2 mutations in the Env protein
Inhibitor | gp41 mutations | Report | |
|---|---|---|---|
T20 | HR1 | HR2 | Â |
T20 | V38A (GIA) | N126K (SKY) | Baldwin et al, 2004 Ray et al, 2007 |
M87 (membrane anchored T20) | I48V | N126K | Hildinger et al, 2001 |
C34 | I37K | N126K | Nameki et al, 2005 |
Retrocyclin RC-101 | Q66R | N126K | Cole et al, 2006 |
T20 | N43D | S138A | Xu et al, 2005 Perez-Alvarez et al, 2006 Ray et al, 2007 |
T20 | N43D | E137K | Tolstrup et al, 2007 |