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Figure 5 | Retrovirology

Figure 5

From: The contribution of peroxynitrite generation in HIV replication in human primary macrophages

Figure 5

MnTBAP inhibits nitrotyrosine formation in HIV-infected macrophages. Photomicrographs (optical microscopy) of nitrotyrosine staining in HIV-1-infected macrophages. HIV-1 infection enhance the immunocytochemical expression of nitrotyrosine (Panel A) in compared to mock-infected macrophages (Panel B), indicating an increased production of peroxynitrite. Acute treatment with MnTBAP (30 μM) (Panel D), but not with AZT (0.05 μM) (Panel C) is able to inhibit in macrophages HIV-related peroxynitrite formation.

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