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Figure 3 | Retrovirology

Figure 3

From: Unintegrated HIV-1 provides an inducible and functional reservoir in untreated and highly active antiretroviral therapy-treated patients

Figure 3

Mobilization of the functional preintegration reservoir. Resting CD4+ T lymphocytes secreting HIV-1 viral proteins in untreated (A) and HAART-treated patients (B). The CD4+ T lymphocytes were polyclonally activated and cultured with 1 μg/ml of enfuvirtide and with or without 40 μM of the HIV-1 integrase inhibitor L-731,988. The median values are shown as black bars. Comparison of results was done by the Wilcoxon signed-rank test.

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