Skip to main content

Table 1 Sequence comparison between the passage of 293.10 for 206 days with or without CQ

From: Effect of chloroquine on reducing HIV-1 replication in vitro and the DC-SIGN mediated transfer of virus to CD4+T-lymphocytes

   

day 206 of passage

 
 

gp120 region

293.10

CQ (#)

Control (#)

P value

 

V1V2

0

1.33 (± 0.52)

0 (± 0)

0.001 *

Charge

V3

4

4 (± 0)

4.85 (± 0.36)

< 0.0001 *

 

V4

-2

-2 (± 0)

-2 (± 0)

equal

 

V1V2

76

76 (± 0)

76 (± 0)

equal

Length

V3

36

36 (± 0)

36 (± 0)

equal

 

V4

28

23(± 0)

28 (± 0)

< 0.0001 *

no. of

V1V2

7

6.67 (± 0.52)

7 (± 0)

0.24

N-glycosylation

V3

2

0 (± 0)

1.69 (± 0.75)

< 0.0001 *

Sites

V4

3

2 (± 0)

2.5 (± 0.58)

0.09

  1. charge, length and potential N-glycosylation sites were determined from the amino acid sequences
  2. # Standard deviations
  3. * P values are considered significant