Table 2 Quantitative analysis of virus core morphology of NC mutant HIV-1 particles produced by HeLaP4 cells
From: Intracellular HIV-1 Gag localization is impaired by mutations in the nucleocapsid zinc fingers
Dense cone shape core | Dense material in base of cone | Round centered core | Round displaced core | Tubular core structure | Two core structures or membrane* | No defined core | Diameter of particles | |
|---|---|---|---|---|---|---|---|---|
wt | 19 | 38 | 21 | 1 | 0 | 7 | 113 ± 4 | |
H23C | 7 | 16 | 16 | 40,5 | 6 | 0 | 14,5 | 134 ± 14 |
H44C | 1 | 7 | 5 | 45 | 13 | 1 | 28 | 129 ± 14 |
H23-H44C | 0 | 0 | 13 | 16 | 23 | 15* | 33 | 96 ± 12 |
ΔZF1 | 6 | 16 | 15 | 39 | 4 | 0 | 20 | 131 ± 12 |
ΔZF2 | 1 | 8 | 3 | 62 | 6 | 2 | 17 | ND |
ΔZF1-ZF2 | 1 | 0 | 11 | 23,5 | 13 | 22,5* | 29 | 101 ± 13 |