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Table 2 Quantitative analysis of virus core morphology of NC mutant HIV-1 particles produced by HeLaP4 cells

From: Intracellular HIV-1 Gag localization is impaired by mutations in the nucleocapsid zinc fingers

  Dense cone shape core Dense material in base of cone Round centered core Round displaced core Tubular core structure Two core structures or membrane* No defined core Diameter of particles
wt 19   38 21 1 0 7 113 ± 4
H23C 7 16 16 40,5 6 0 14,5 134 ± 14
H44C 1 7 5 45 13 1 28 129 ± 14
H23-H44C 0 0 13 16 23 15* 33 96 ± 12
ΔZF1 6 16 15 39 4 0 20 131 ± 12
ΔZF2 1 8 3 62 6 2 17 ND
ΔZF1-ZF2 1 0 11 23,5 13 22,5* 29 101 ± 13
  1. Number of particles observed: 80 to 200. Numbers are expressed in % of total observed particles.