Table 4 Frequency of proviral insertions within defined genomic regions
Virus | Upstreama | Promoterb | 1. intron | Internal intron | Last intron | Downstreamc | Exon | Outsided | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
+ | - | + | - | + | - | + | - | + | - | + | - | + | - | ||
Akv-wt | 2/104 2% | 7/104 7% | 5/104 5% | 3/104 3% | 9/104 9% | 16/104 15% | 6/104 6% | 17/104 16% | 2/104 2% | 1/104 1% | 5/104 5% | 8/104 8% | 2/104 2% | 1/104 1% | 11/104 10% |
Akv-CD | 3/46 7% | 6/46 13% | 1/46 2% | 0/46 0% | 3/46 7% | 5/46 11% | 2/46 4% | 8/46 17% | 0/46 0% | 0/46 0% | 4/46 9% | 6/46 13% | 1/46 2% | 0/46 0% | 5/46 11% |
Akv-EH | 3/51 6% | 4/51 8% | 1/51 2% | 0/51 0% | 4/51 8% | 6/51 12% | 2/51 4% | 11/51 22% | 2/51 4% | 0/51 0% | 7/51 14% | 1/51 2% | 2/51 4% | 2/51 4% | 6/51 12% |
Akv-CDH | 1/39 3% | 2/39 5% | 2/39 5% | 3/39 8% | 7/39 18% | 3/39 8% | 3/39 8% | 5/39 13% | 0/39 0% | 1/39 3% | 5/39 13% | 4/39 10% | 0/39 0% | 0/39 0% | 3/39 8% |
Total | 9/240 4% | 19/240 8% | 9/240 4% | 6/240 3% | 23/240 10% | 30/240 13% | 13/240 5% | 41/240 17% | 4/240 2% | 2/240 1% | 21/240 9% | 19/240 8% | 5/240 2% | 3/240 1% | 25/240 10% |