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Table 4 Frequency of proviral insertions within defined genomic regions

From: Impairment of alternative splice sites defining a novel gammaretroviral exon within gagmodifies the oncogenic properties of Akv murine leukemia virus

Virus Upstreama   Promoterb   1. intron   Internal intron   Last intron   Downstreamc   Exon   Outsided
  + - + - + - + - + - + - + -  
Akv-wt 2/104 2% 7/104 7% 5/104 5% 3/104 3% 9/104 9% 16/104 15% 6/104 6% 17/104 16% 2/104 2% 1/104 1% 5/104 5% 8/104 8% 2/104 2% 1/104 1% 11/104 10%
Akv-CD 3/46 7% 6/46 13% 1/46 2% 0/46 0% 3/46 7% 5/46 11% 2/46 4% 8/46 17% 0/46 0% 0/46 0% 4/46 9% 6/46 13% 1/46 2% 0/46 0% 5/46 11%
Akv-EH 3/51 6% 4/51 8% 1/51 2% 0/51 0% 4/51 8% 6/51 12% 2/51 4% 11/51 22% 2/51 4% 0/51 0% 7/51 14% 1/51 2% 2/51 4% 2/51 4% 6/51 12%
Akv-CDH 1/39 3% 2/39 5% 2/39 5% 3/39 8% 7/39 18% 3/39 8% 3/39 8% 5/39 13% 0/39 0% 1/39 3% 5/39 13% 4/39 10% 0/39 0% 0/39 0% 3/39 8%
Total 9/240 4% 19/240 8% 9/240 4% 6/240 3% 23/240 10% 30/240 13% 13/240 5% 41/240 17% 4/240 2% 2/240 1% 21/240 9% 19/240 8% 5/240 2% 3/240 1% 25/240 10%
  1. a Within 3–100 kb upstream of target gene/RefSeq
  2. b Within 0–3 kb upstream of exon1 of target gene/RefSeq
  3. c Within 100 kb downstream of target gene/RefSeq
  4. d Proviral integrations > 100 kb away from gene/RefSeq
  5. + or - denotes the orientation of the integrated provirus relative to the target gene/RefSeq.