Table 1 Cytokine Profile for HIV-based Particles
| Â | Â | Particle Preparations | Time Points | ||
|---|---|---|---|---|---|
Cytokine | Culture Treatment1 | Virus | Modification | 6 Day | 13 Day |
IFN-γ pg/ml | Unstimulated | no particles | NA2 | 810 | ND3 |
| Â | PHA-stimulated | no particles | NA | >2,000 | ND |
| Â | Unstimulated | HIV-1 | non-engineered | 450 | 650 |
| Â | Unstimulated | HIV-1 | B7-engineered | >2,000 | >2,000 |
| Â | Unstimulated | HIV-1 | B7+antiCD3 | >2,000 | >2,000 |
IL-10 pg/ml | Unstimulated | no particles | NA | 50 | ND |
| Â | PHA-stimulated | no particles | NA | 150 | ND |
| Â | Unstimulated | HIV-1 | non-engineered | 70 | 50 |
| Â | Unstimulated | HIV-1 | B7-engineered | 40 | 25 |
| Â | Unstimulated | HIV-1 | B7+antiCD3 | 30 | 30 |
IL-4 pg/ml | Unstimulated | no particles | NA | <10 | ND |
| Â | PHA-stimulated | no particles | NA | <10 | ND |
| Â | Unstimulated | HIV-1 | non-engineered | <10 | <10 |
| Â | Unstimulated | HIV-1 | B7-engineered | <10 | <10 |
| Â | Unstimulated | HIV-1 | B7+antiCD3 | <10 | <10 |