Skip to main content
Figure 6 | Retrovirology

Figure 6

From: Sequential emergence and clinical implications of viral mutants with K70E and K65R mutation in reverse transcriptase during prolonged tenofovir monotherapy in rhesus macaques with chronic RT-SHIV infection

Figure 6

Kinetics of K70E and K65R RT mutants during tenofovir therapy. Twelve RT-SHIV infected macaques were started on tenofovir treatment 5 months after infection. Real-time PCR technology was used to quantitate K65R and K70E RT mutants in plasma samples; values are expressed as percentage of total viral RNA copy number. At the onset of tenofovir therapy (i.e, baseline, BL), no K65R and K70E virus could be detected. The red and blue circles indicate the first detection of K70E and K65R, respectively; weeks indicate weeks of tenofovir treatment.

Back to article page

Retrovirology

ISSN: 1742-4690

Contact us