The HBZ-SP1 protein dynamically associates with subnuclear foci in living cells in a C-terminus-dependent mechanism. COS cells were transiently transfected with EGFP-HBZ-SP1 or EGFP-HBZ-SP1ΔZIP. Pre-bleached images are shown. The arrows show the photobleached foci for which the recovery rates were determined. The images shown were captured before photobleaching (Pre-bleach) and at the indicated time points (Post-bleach). The white bars correspond to a scale of 10 μm. Recovery curves of the proteins are shown as relative fluorescence intensity vs. time.