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Table 4 SIV-specific CD8+ T cell responses before and after SIVmac055 challenge

From: Tenofovir treatment augments anti-viral immunity against drug-resistant SIV challenge in chronically infected rhesus macaques

Macaque

Daya

SIVenvb

SIVgagb

SIVpolb

SIVnefb

Tenofovirc

1494

(-35)

60

240

155

95

No

 

(-15)

160

520

220

205

 
 

9

45

255

115

120

 
 

265

35

180

40

90

 

1512

(-35)

30

290

190

50

No

 

(-15)

25

105

115

35

 
 

9

40

95

60

15

 
 

265

475

545

440

349

 

1488

(-35)

620

170

10

50

Yes

 

(-15)

2365

510

70

80

 
 

9

1533

458

83

168

 
 

265

3305

1335

205

160

 

1514

(-35)

85

190

15

15

Yes

 

(-15)

245

380

60

30

 
 

9

65

85

25

0

 
 

265

265

535

55

70

 
  1. aDays before and after SIVmac055 challenge
  2. bData is expressed as the number of spot-forming cells (SFC) per 106 PBMC
  3. cTenofovir treatment for a total of 6 weeks at a dose of 30 mg/kg of body weight
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Retrovirology

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