Figure 3
Effect of tenofovir on plasma viral load in macaques infected with SIVmac251 or SIVmac239Δnef. Rhesus macaques with chronic SIV infection were treated for 6 weeks with tenofovir at a dose of 30 mg/kg body weight. The effect on SIV replication was determined by quantification of plasma SIV RNA by allele-specific real-time PCR. Plasma viral load is expressed as SIV RNA copies/ml and shown for macaques with replicating (A) SIVmac251 and (B) SIVmac239Δnef.