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Figure 4 | Retrovirology

Figure 4

From: Lung cancer induced in mice by the envelope protein of jaagsiekte sheep retrovirus (JSRV) closely resembles lung cancer in sheep infected with JSRV

Figure 4

Fibroblastic cell masses found in some JSRV-infected sheep. Left panels show Mab C9 staining and right panels show hematoxylin and eosin staining of sheep lung sections. Panels A and B show a round proliferative fibroblastic cell mass (myxomatous tissue) flanked at upper right and left by typical epithelial tumors from South African sheep 96238. Panels C and D show magnified views of the fibroblastic cell mass corresponding to the boxed areas in Panels A and B. Panel E shows Env staining of a large fibroblastic cell mass from naturally-infected United States sheep 85RS65. Panel F shows connective tissue containing fibroblasts at the edge of the lung from South African sheep 93141. These cells were all Env-negative (not shown).

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Retrovirology

ISSN: 1742-4690

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